Correlation Between Lipid Profile and Acne Vulgaris

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Mohammadreza Sobhan, 1 Mohammad Ali Seif Rabiei, 2 Maryam Amerifar 1

1Psoriasis Research Center, Department of Dermatology, Sina Hospital, Hamadan University of Medical Sciences, Hamadan, Iran; 2Department of Social Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

Correspondence: Mohammadreza Sobhan
Psoriasis Research Center, Department of Dermatology, Sina Hospital, Hamadan University of Medical Sciences, Mirzade Eshghy Street, Hamadan 65168408741, Iran
Tel +989121089455
Fax +988138269808
Email mreza_sobhan@yahoo.com

Background and Aim: Acne is a common skin disease resulting from a complex interaction of various pathogenetic factors. The aim of this study was to find out lipid profile abnormalities in acne vulgaris patients.
Material and Methods: This descriptive analytic cross-sectional study was conducted on 45 acne patients and 45 age- and sex-matched healthy controls to assess plasma total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels.
Results: We showed a higher cholesterol level in acne patients (P=0.025), particularly in men (P=0.04). Other plasma lipids including TG, LDL, and HDL in male and female patients were higher compared to controls, but this is not statistically significant.
Discussion and Conclusion: In conclusion, lipid profile was altered in our patients, with high cholesterol level as the commonest derangement, particularly in men. Therefore, screening for lipid profile abnormalities could be considered in the treatment of acne patients.

Keywords: acne vulgaris, lipid profile, severity


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